EpidemiologyMatters

A way of seeing

Almost everything you believe about your health began as a pattern in a population.

Does coffee harm you? Does a drug work? Is the air safe? Every answer we trust came from someone comparing groups of people and asking whether the difference was real — or a trick of the data. That discipline is epidemiology, and this is where you learn to see it.

  • The spineThe Oxford textbook by Keyes, Abba-Aji & Galea
  • The reachWritten for anyone curious, at any level
  • The methodPlayable populations, not memorized formulas
See it for yourself

Proof · 60 seconds

Does coffee cause heart attacks?

240 people in FarrlandiaTap through the story →
Smokers
Non-smokers

For Students

Learn epidemiology by doing. Manipulate populations, observe associations, introduce bias, and see what happens. No formulas required to start — just curiosity.

For Instructors

Replace a lecture with a live demonstration. Use preset scenarios to show confounding, Simpson's paradox, or selection bias in real time. Assign interactive exercises tied to each chapter.

For Everyone

Epidemiology shapes policy, headlines, and daily life. Understand how we know what causes disease — and why it matters who we study and how we study them.

The Framework

Seven Steps for an Epidemiology of Consequence

The book organizes epidemiologic thinking around seven foundational steps. Each builds on the last. Together, they constitute a complete framework for studies that matter.

1
Define the population
2
Measure exposures & outcomes
3
Take a sample
4
Estimate associations
5
Evaluate causality
6
Assess interaction
7
Assess external validity

New in the Second Edition

Consequence Boxes

Each chapter connects a methodological choice to a question of social responsibility.

◆ Chapter 3: Measurement

How we define a health indicator determines who counts as a case. Who counts determines what risk factors we find. What we find determines what gets funded.

Consider depression. A clinical interview identifies fewer cases than a screening tool. Those missed are disproportionately people without access to clinical settings. The measurement choice is not neutral.

When you choose a measure, ask: whose health does this make visible, and whose does it obscure?

Launching Fall 2028

The Farrlandia Challenge

An inter-school competition for public health students. Investigate an outbreak in Farrlandia. Identify causes. Propose interventions. Compete against teams from schools across the country.

L. Graunt Port Snow Farr Harbour Graunt Fields Nightingale Point Hill Crossing THE ISLE OF FARRLANDIA POPULATION 1,000 • EVERY RESIDENT KNOWN N 0 10 leagues reported case resident, well post road
The Isle of Farrlandia — named for William Farr, founder of modern vital statistics. An outbreak at Port Snow opens the Challenge.

4 Rounds, 4 Weeks

Each round follows the seven-step framework: define, investigate, challenge, intervene.

Real Tools

Teams use the platform's interactive modules to analyze the Farrlandia dataset.

Free to Enter

Open to any team of 3–5 students enrolled in a public health program.

Consequentialist Scoring

Judged on rigor, population impact, communication, and creativity.

The Authors

Keyes, Abba-Aji, and Galea

KK
Katherine M. Keyes, PhD
Professor of EpidemiologyDirector, Brody Center for Population Mental HealthColumbia University
Faculty Profile →
MA
Mohammed Abba-Aji, MD, MPH, DrPH
Postdoctoral Researcher & LecturerWashington UniversitySchool of Public Health
Faculty Profile →
SG
Sandro Galea, MD, DrPH
Margaret C. Ryan DeanWashington UniversitySchool of Public Health
Faculty Profile →

The Book · Second Edition · Coming 2028

Epidemiology Matters

Everything you just played is drawn from the textbook by Keyes, Abba-Aji, and Galea, published by Oxford University Press. The print edition carries QR codes that open each interactive module. Be the first to know when it launches.

Stay Updated

Get notified when new tools launch, when the Farrlandia Challenge opens, and when the second edition is available.